Bush has just vetoed legislation that would have expanded federal funding for embryonic stem cell research. It was the first veto in the 5 and a half years of the Bush presidency, but Bush did it privately, with press photographers barred from the event.
The majority of Americans support stem cell research, including many Republicans. The Senate is four votes shy of a Veto Override (2/3 majority), so it will probably stand, though.
I would dearly love to see this turn and bite him on the ass, as non-Religious-Lunatic Republicans say “enough is enough,” and cast off the stranglehold that the American Taliban has on their party, but it will most likely be buried under an avalanche of Israel/Lebanon coverage.